| 5 | Sigmatex UK Ltd (Staff Restaurant) | Restaurant/Cafe/Canteen | Halton | WA7 1TE |
| 5 | Simms Cross Institute | Pub/bar/nightclub | Halton | WA8 6PN |
| 5 | Simonsfield Residential Home | Hospitals/Childcare/Caring Premises | Halton | WA7 5XE |
| 5 | Simply Sandwiches | Takeaway/sandwich shop | Halton | WA8 9LG |
| 5 | Sizzles Cafe. Boss Burger. Shake & Waffle. | | Other catering premises | Halton | WA7 4UD |
| 5 | Small Batch Brewing Company | Manufacturers/packers | Halton | WA7 |
| 5 | Small Batch Tap Room | Manufacturers/packers | Halton | WA7 1HU |
| 5 | Smithy Forge Residential Home | Hospitals/Childcare/Caring Premises | Halton | WA7 6PZ |
| Exempt | Sophia House | Hospitals/Childcare/Caring Premises | Halton | WA8 |
| Awaiting | Sorriso Pizza | Takeaway/sandwich shop | Halton | WA7 1AE |
| 4 | Space RUNCORN CIC | Restaurant/Cafe/Canteen | Halton | WA7 1LJ |
| 5 | Spar | Retailers - other | Halton | WA8 8RF |
| 3 | Spar | Retailers - other | Halton | WA7 2NZ |
| 5 | Spar Convenience Store | Retailers - other | Halton | WA8 0TT |
| 5 | Spar Shop | Retailers - other | Halton | WA7 3AL |
| 5 | Spar at Rockmount Service Station | Retailers - other | Halton | WA7 5SP |
| 5 | Spinney Pre-School | Hospitals/Childcare/Caring Premises | Halton | WA8 8LD |
| 5 | Spoon Desserts NW Ltd | Mobile caterer | Halton | WA7 |
| Exempt | Sports Direct | Retailers - other | Halton | WA7 2QF |
| 5 | Spud Shack | Mobile caterer | Halton | - |
| 5 | St Andrews Church | Hospitals/Childcare/Caring Premises | Halton | WA7 5JZ |
| 5 | St Augustine's Catholic Primary School & Nursery - Impact Food Group | School/college/university | Halton | WA7 2JJ |
| 5 | St Basil's & All Saints Parish Centre | Pub/bar/nightclub | Halton | WA8 4SZ |
| 5 | St Basil's Rc Aided Primary School Mellors Catering | School/college/university | Halton | WA8 4SZ |
| 5 | St Bede's Catholic Primary School - Mellors | School/college/university | Halton | WA8 6EL |
| 5 | St Berteline And St Christopher Church Cafe | Other catering premises | Halton | WA7 6QE |
| 5 | St Berteline's Primary School - Orian Catering | School/college/university | Halton | WA7 6QN |
| 5 | St Clements Rc Aided Primary School - Edsential | School/college/university | Halton | WA7 4NX |
| 5 | St Edward's Catholic Primary School - Breakfast Club | Hospitals/Childcare/Caring Premises | Halton | WA7 1RZ |
| 5 | St Edward's Catholic Primary School - Edsential | School/college/university | Halton | WA7 1RZ |
| 5 | St Gerard's RC Primary & Nursery School Dolce Catering | School/college/university | Halton | WA8 6DD |
| 5 | St John Fisher Extra Club | Hospitals/Childcare/Caring Premises | Halton | WA8 0BW |
| 5 | St John Fisher Primary School - Dolce Ltd | School/college/university | Halton | WA8 0BW |
| 5 | St Johns Church Pre School | Hospitals/Childcare/Caring Premises | Halton | WA8 6HA |
| 5 | St Lukes Nursing Home | Hospitals/Childcare/Caring Premises | Halton | WA7 2SU |
| 5 | St Martins Breakfast and AfterSchool Club | Hospitals/Childcare/Caring Premises | Halton | WA7 6HZ |
| 5 | St Martins R C Primary School Edsential Catering | School/college/university | Halton | WA7 6HZ |
| 5 | St Mary's C Of E School Orian Catering | School/college/university | Halton | WA7 2NR |
| 5 | St Michael with St Thomas CE Primary School | School/college/university | Halton | WA8 8LD |
| 5 | St Michaels News (Best One) | Retailers - other | Halton | WA8 8TA |
| 5 | St Patricks Residential Care Home | Hospitals/Childcare/Caring Premises | Halton | WA8 3PN |
| Exempt | St. Ambrose Church and Hall | Other catering premises | Halton | WA8 0QA |
| 5 | St. Michaels Catholic Primary - Edsential | School/college/university | Halton | WA8 8TD |
| 5 | St.Michaels Extended School | Hospitals/Childcare/Caring Premises | Halton | WA8 8TD |
| 5 | Stantons of Cheshire | Retailers - other | Halton | WA8 8TL |
| 5 | Starbucks | Restaurant/Cafe/Canteen | Halton | WA7 5AQ |
| Exempt | Store Twenty One | Retailers - other | Halton | WA7 2EU |
| 3 | Street Front | Restaurant/Cafe/Canteen | Halton | WA8 0NQ |
| 5 | Subway | Takeaway/sandwich shop | Halton | WA8 6BL |
| 5 | Subway | Takeaway/sandwich shop | Halton | WA7 5AQ |