| 4 | Shanthi's Kitchen | Other catering premises | Harborough | LE8 |
| Exempt | Sharon Wright Slimming World | Retailers - other | Harborough | LE16 8SN |
| 5 | Shearsby Bath | Restaurant/Cafe/Canteen | Harborough | LE17 6PP |
| 5 | Shearsby Valley Tackle Ltd | Retailers - other | Harborough | LE17 6PX |
| 5 | Sherrier C Of E Primary School | School/college/university | Harborough | LE17 4EX |
| 5 | Shoulder Of Mutton | Pub/bar/nightclub | Harborough | LE16 7RB |
| Exempt | Slimming World | Retailers - other | Harborough | LE9 6RH |
| Exempt | Slimming World | Other catering premises | Harborough | LE16 |
| Exempt | Slimming World | Retailers - other | Harborough | LE8 8AJ |
| 5 | Smash \& Scoop | Retailers - other | Harborough | LE17 4AD |
| 5 | Smiles Gilmorton | School/college/university | Harborough | LE17 5LU |
| 5 | Smiths Amusements Candy Cottage | Mobile caterer | Harborough | LE17 |
| 5 | Sodexo LGS Stoneygate School | School/college/university | Harborough | LE8 9DJ |
| 5 | Sophie Deeks | Mobile caterer | Harborough | LE17 |
| 5 | South Kilworth Church Of England Primary School | School/college/university | Harborough | LE17 6EG |
| 5 | Spar | Retailers - other | Harborough | LE16 9BX |
| 5 | Spar | Retailers - other | Harborough | LE9 6NQ |
| 5 | Springfields Supermarkets LTD | Retailers - other | Harborough | LE17 6LH |
| 5 | Sprinkles And Toppers | Retailers - other | Harborough | LE17 |
| 5 | Squeakies Children's Nursery | Hospitals/Childcare/Caring Premises | Harborough | LE8 0RB |
| 5 | St Andrews Childcare | Hospitals/Childcare/Caring Premises | Harborough | LE17 6HD |
| 5 | St Andrews Church Of England Primary School | School/college/university | Harborough | LE17 6HD |
| 5 | St Catharine's Church | Restaurant/Cafe/Canteen | Harborough | LE7 9GD |
| 5 | St Cuthberts C Of E School | School/college/university | Harborough | LE8 9EQ |
| 5 | St Josephs Breakfast \& Afterschool Club | Hospitals/Childcare/Caring Premises | Harborough | LE16 9QQ |
| 5 | St Josephs Catholic Voluntary Academy | School/college/university | Harborough | LE16 9BZ |
| 5 | St Lukes C Of E Primary School | School/college/university | Harborough | LE7 9PN |
| 5 | St Lukes Hospital | Hospitals/Childcare/Caring Premises | Harborough | LE16 7BN |
| 5 | St Marys C Of E School | School/college/university | Harborough | LE17 4SB |
| 4 | St Marys Fish Bar | Takeaway/sandwich shop | Harborough | LE16 7DX |
| 5 | St Marys Montessori | Hospitals/Childcare/Caring Premises | Harborough | LE17 4SH |
| 5 | Staff Of Life | Pub/bar/nightclub | Harborough | LE17 6NT |
| 5 | Starbucks | Restaurant/Cafe/Canteen | Harborough | LE16 7DS |
| Exempt | Stretton 2000 Limited | Restaurant/Cafe/Canteen | Harborough | LE2 2FG |
| 5 | Stuart Court | Hospitals/Childcare/Caring Premises | Harborough | LE8 0LR |
| 5 | Stuarts Place | Mobile caterer | Harborough | LE17 |
| 5 | Su&shi | Restaurant/Cafe/Canteen | Harborough | LE16 9AA |
| 5 | Subway | Takeaway/sandwich shop | Harborough | LE17 4AT |
| 5 | Subway | Takeaway/sandwich shop | Harborough | LE16 7AP |
| 5 | Suchs Donuts | Mobile caterer | Harborough | LE17 |
| 5 | Sue's Cheese Stall | Retailers - other | Harborough | LE16 9HB |
| 5 | Sues Homemade Cakes | Other catering premises | Harborough | LE17 |
| 5 | Sugar Rush Bakes | Retailers - other | Harborough | LE8 |
| 3 | Sunargow Tandoori Restaurant | Restaurant/Cafe/Canteen | Harborough | LE9 6RE |
| 5 | Sunnybrae Service Station | Retailers - other | Harborough | LE7 9HJ |
| 5 | Super Star Sport Midlands LTD | School/college/university | Harborough | LE16 7SZ |
| 5 | Sutton Circuit | Restaurant/Cafe/Canteen | Harborough | - |
| 5 | Sutton In The Elms Care Home | Hospitals/Childcare/Caring Premises | Harborough | LE9 6QF |
| 5 | Swallow Cottage | Takeaway/sandwich shop | Harborough | LE16 9BZ |
| 5 | Sweet Cake Co | Other catering premises | Harborough | LE7 |