| Exempt | Slimming World | Retailers - other | Oadby and Wigston | LE2 |
| 5 | Small Fry | Other catering premises | Leicester City | LE2 |
| 5 | Smash N Grub | Takeaway/sandwich shop | Leicester City | LE2 0DT |
| 5 | Smiley Kidz Nursery | Hospitals/Childcare/Caring Premises | Leicester City | LE2 0GU |
| 5 | Soar Point | Pub/bar/nightclub | Leicester City | LE2 7BY |
| 5 | Sodexo Government Services At Kirk Lodge | Hospitals/Childcare/Caring Premises | Leicester City | LE2 2PJ |
| 4 | Sofia's Coffee | Restaurant/Cafe/Canteen | Leicester City | LE2 1HG |
| 5 | South Lodge | Hospitals/Childcare/Caring Premises | Leicester City | LE2 3ND |
| 4 | Sparken Wine Supermarket | Retailers - other | Leicester City | LE2 0TA |
| 5 | Sparkenhoe Community Primary School | School/college/university | Leicester City | LE2 0NE |
| 5 | Sparkenhoe Community Primary School | School/college/university | Leicester City | LE2 0DL |
| 5 | Spice Bazzar | Restaurant/Cafe/Canteen | Leicester City | LE2 6EH |
| 5 | Spice Hub | Restaurant/Cafe/Canteen | Leicester City | LE2 1EG |
| 5 | Spice Jar Kitchen | Takeaway/sandwich shop | Oadby and Wigston | LE2 |
| 5 | Spicy Smash | Takeaway/sandwich shop | Leicester City | LE2 6BJ |
| 5 | Spire Leicester Hospital | Hospitals/Childcare/Caring Premises | Oadby and Wigston | LE2 2FG |
| 5 | Spring Jiangnan | Restaurant/Cafe/Canteen | Leicester City | LE2 7AB |
| Awaiting | Springfield House Residential Care Home | Hospitals/Childcare/Caring Premises | Leicester City | LE2 3BA |
| 5 | St Georges | Hospitals/Childcare/Caring Premises | Leicester City | LE2 3TE |
| 5 | St Georges Nursery School | Hospitals/Childcare/Caring Premises | Oadby and Wigston | LE2 5QF |
| 5 | St Johns Breakfast Club | School/college/university | Leicester City | LE2 1TE |
| 3 | St Peters Service Station | Retailers - other | Leicester City | LE2 1DA |
| Exempt | St Stephens Chemist | Retailers - other | Leicester City | LE2 1GH |
| 5 | St Thomas More Afterschool Club | School/college/university | Leicester City | LE2 3TA |
| 5 | St. Andrews Play Association / SAPA Community Pantry | Distributors/Transporters | Leicester City | LE2 7LA |
| 5 | St. Georges Nursery School | Hospitals/Childcare/Caring Premises | Leicester City | LE2 8AD |
| 5 | St. John The Baptist C Of E Primary School | School/college/university | Leicester City | LE2 1TE |
| 5 | St. Thomas More Catholic Voluntary Academy | School/college/university | Leicester City | LE2 3TA |
| 5 | Starbucks | Restaurant/Cafe/Canteen | Oadby and Wigston | LE2 4LA |
| 4 | Station Mini Market | Retailers - other | Leicester City | LE2 0JN |
| 5 | Steakhouse | Restaurant/Cafe/Canteen | Leicester City | LE2 1QJ |
| 5 | Step In | Retailers - other | Leicester City | LE2 6UG |
| 5 | Step In Off Licence | Retailers - other | Leicester City | LE2 7DU |
| 5 | Stonesby Care Home | Hospitals/Childcare/Caring Premises | Leicester City | LE2 6TY |
| 4 | Stonesby House | Hospitals/Childcare/Caring Premises | Leicester City | LE2 6TY |
| 5 | Stonesby House | Hospitals/Childcare/Caring Premises | Leicester City | LE2 6TY |
| 5 | Stoneygate | Hospitals/Childcare/Caring Premises | Leicester City | LE2 2AD |
| 5 | Stoneygate Ashlands | Hospitals/Childcare/Caring Premises | Leicester City | LE2 3TE |
| 5 | Stoneygate Montessori By Ashbourne | Hospitals/Childcare/Caring Premises | Leicester City | LE2 3BE |
| 5 | Stoneygate Oaklands | Hospitals/Childcare/Caring Premises | Leicester City | LE2 2PJ |
| Exempt | Stretton 2000 Limited | Restaurant/Cafe/Canteen | Harborough | LE2 2FG |
| 5 | Sturdee Community Hospital | Hospitals/Childcare/Caring Premises | Leicester City | LE2 9FS |
| 3 | Subway | Restaurant/Cafe/Canteen | Oadby and Wigston | LE2 5BF |
| 5 | Subway | Restaurant/Cafe/Canteen | Leicester City | LE2 1TU |
| 5 | Subway | Retailers - other | Leicester City | LE2 8JB |
| 5 | Subway | Takeaway/sandwich shop | Leicester City | LE2 8JB |
| 5 | Subway | Takeaway/sandwich shop | Leicester City | LE2 6UF |
| 5 | Subway At De Montfort University | Restaurant/Cafe/Canteen | Leicester City | LE2 7DR |
| 5 | Subway At One Stop | Restaurant/Cafe/Canteen | Leicester City | LE2 1HH |
| 3 | Sugar Momma Leicester | Takeaway/sandwich shop | Leicester City | LE2 1HF |