- Reach Social Enterprises Ltd4Restaurant/Cafe/CanteenSouthamptonSO17 2LJ
- Rio's Piri Piri4Restaurant/Cafe/CanteenSouthamptonSO17 2NG
- Romanian Flavours Ltd5Restaurant/Cafe/CanteenSouthamptonSO17 2WE
- SNS Sravs Kitchen Ltd, Trading As Sravs Kitchen4Takeaway/sandwich shopSouthamptonSO17 2NJ
- SUSU Shop5Retailers - otherSouthamptonSO17 1BJ
- Sainsbury's5Retailers - supermarkets/hypermarketsSouthamptonSO17 2LB
- Sam Store5Retailers - otherSouthamptonSO17 2FW
- Sam's Chicken Ltd5Restaurant/Cafe/CanteenSouthamptonSO17 2NF
- Scoops Gelato5Restaurant/Cafe/CanteenSouthamptonSO17 2NG
- Shaftesbury Rest Home5Hospitals/Childcare/Caring PremisesSouthamptonSO17 1SE
- Shawarma Xpress4Restaurant/Cafe/CanteenSouthamptonSO17 2FY
- Shell Swaythling5Retailers - otherSouthamptonSO17 3ED
- Smokey Pizza5Takeaway/sandwich shopSouthamptonSO17 2ES
- Smokeys Burgers and Shakes4Restaurant/Cafe/CanteenSouthamptonSO17 2FY
- South Western Arms4Pub/bar/nightclubSouthamptonSO17 2HW
- Southampton Mencap EnterprisesAwaitingRetailers - otherSouthamptonSO17 2NF
- Springs Residential Care Home5Restaurant/Cafe/CanteenSouthamptonSO17
- Sprinkles Gelato4Retailers - otherSouthamptonSO17 2NJ
- St Denys Church Centre5Other catering premisesSouthamptonSO17 2ND
- St Denys Convenience Store5Retailers - otherSouthamptonSO17 2FS
- St Denys Primary School5School/college/universitySouthamptonSO17 2ND
- St. Annes Nursing Home5Hospitals/Childcare/Caring PremisesSouthamptonSO17 2EX
- Stags Head5Pub/bar/nightclubSouthamptonSO17 1BJ
- Sticky Fingers Pre-School PortswoodAwaitingSchool/college/universitySouthamptonSO17 3AA
- Subway5Restaurant/Cafe/CanteenSouthamptonSO17 2NH
- Sushi Gourmet5Takeaway/sandwich shopSouthamptonSO17 2LB
- Suzi's Snack Shack4Mobile catererSouthamptonSO17 3AN
- Swaythling Primary School5School/college/universitySouthamptonSO17 3SZ
- Sweet Bakes5Other catering premisesSouthamptonSO17
- T Rex Supermarket5Retailers - supermarkets/hypermarketsSouthamptonSO17 2NJ
- TLC BakesAwaitingOther catering premisesSouthamptonSO17
- Taning5Restaurant/Cafe/CanteenSouthamptonSO17 1BJ
- Terrace Restaurant5Restaurant/Cafe/CanteenSouthamptonSO17 1BJ
- The Atrium CafeAwaitingRestaurant/Cafe/CanteenSouthamptonSO17 1TL
- The Avenue Chinese Takeaway5Takeaway/sandwich shopSouthamptonSO17 1XS
- The Broadway4Pub/bar/nightclubSouthamptonSO17 2NH
- The Brook4Pub/bar/nightclubSouthamptonSO17 3SD
- The Crown Inn3Pub/bar/nightclubSouthamptonSO17 1QE
- The Curry Man5Mobile catererSouthamptonSO17 3SG
- The Dolphin St Denys5Pub/bar/nightclubSouthamptonSO17 2EZ
- The Drummond Arms3Pub/bar/nightclubSouthamptonSO17 3AA
- The Mitre5Pub/bar/nightclubSouthamptonSO17 2LB
- The Southern Dumpling5Other catering premisesSouthamptonSO17 1RJ
- Trago Lounge5Pub/bar/nightclubSouthamptonSO17 2LB
- University Of Southampton Avenue Lattes5Restaurant/Cafe/CanteenSouthamptonSO17 1BF
- Victory Gospel Church5Restaurant/Cafe/CanteenSouthamptonSO17 2NH
- Vincenzo's5Mobile catererSouthamptonSO17
- Vita Student Portswood5Hotel/bed & breakfast/guest houseSouthamptonSO17 2LB
- Voyage Care - Harefield Lodge5Hospitals/Childcare/Caring PremisesSouthamptonSO17 1DN
- Waitrose Ltd5Retailers - supermarkets/hypermarketsSouthamptonSO17 2FX